Turmeric, the “golden spice” has already been proven as very effective in fighting many diseases. Although these healing properties are usually connected with its well known compound- curcumin, there’s another compound which offers many health benefits too.
That compound is aromatic- turmerone or ar-turmerone. Ar-turmerone is fat- soluble compound found in turmeric. Recently, studies have shown that ar-turmerone is the compound that has positive effects in brain regeneration.
Recovery and Self-Repair of Brain Function
According to a study published in the journal Stem Cell Research & Therapy, scientists from the Institute and Medicine at the Research Centre Juelich in Germany studied the impact that another compound of the turmeric has on neural cells by injecting the compound into rat’s brains.
According to the study, ar-turmerone induces neural stem cell (NSC) proliferation. By promoting endogenous NSC, which are stem cells found in adult brains and which differentiate into neurons, ar-turmerone can be very important in the self-repairing process and recovery of brain function in neurodegenerative diseases.
Neural Stem Cells Produce Neurons
Researchers studied the effects of ar-turmerone on NSC proliferation and differentiation both in vivo and in vitro.
They put rat fetal NSC in six different concentrations of ar-turmerone for over 72 hours. At some concentrations, ar-turmerone was shown to increase NSC proliferation by up to 80% without any impact on cell-death. The cell differentiation process also happened faster at those cells which were treated with ar-turmerone than at those who weren’t.
In order to test the effects of ar-turmerone on NSC in vivo, the researchers injected ar-turmerone in adult rats. They used positron emission tomography (PET) imaging and a tracer to detect proliferation cells, and they found that the subventricular zone (SVZ) was wider, the hippocampus expanded, in the brains of the rats which were injected with ar-turmerone. The SVZ and hippocampus are the two sites in adult mammalian brains where neurogenesis, the growth of neurons, happens.
The lead author of the study Dr. Maria Adele Rueger, said:
“While several substances have been described to promote stem cell proliferation in the brain, fewer drugs additionally promote the differentiation of stem cells into neurons, which constitutes a major goal in regenerative medicine. Our findings on aromatic turmerone take us one step closer to achieving this goal.”
She also added:
“It is interesting that it might be possible to boost the effectiveness of the stem cells with aromatic-turmerone. And it is possible this in turn can help boost repair in the brain.”
Ar-turmerone can also block activation of neuro-inflammatory microglia cells, thus helping to prevent assorted neurological disorders.
Due to its abilities to build neurons from stem cells, scientists see ar-turmerone as very effective in treating conditions like stroke and degenerative diseases like Alzheimer disease and other neurological disorders.
Although, the effects from using ar-turmerone are still relatively unknown and need to be studied further, this study shows that there is definitely a regenerative factor within. So add the whole turmeric into your everyday use and you’ll reap the benefits in the future.
Life enhancement; Turmerone Induces Neural
Stem Cell Proliferation http://www.life-enhancement.com/magazine/article/3260-turmerone-induces-neural-stem-cell-proliferation
My Health Reason; This Is How Your Brain Physically Changes When You Consume Whole Turmeric http://myhealthyreason.com/2016/09/13/brain-physically-changes-consume-whole-turmeric/
BioMed Central; Stem Cell Research & Therapy; Aromatic-turmerone induces neural stem cell proliferation in vitro and in vivo http://stemcellres.biomedcentral.com/articles/10.1186/scrt500#sec5